Yohimbine / NCCIH
Yohimbine is promoted for its fat-burning properties and benefits for male sexual dysfunction. Though yohimbine is effective, side effects may include anxiety, nervousness, and an elevated heart rate, and the reported dose of yohimbine in many supplement formulas doesn’t match the actual dose.
Some evidence supports the use of yohimbine as a natural way to improve symptoms of erectile dysfunction (ED) in men. While studies have questioned this claim, two meta-analyses concluded that yohimbine taken alone or alongside other therapies, including arginine
Arginine
Arginine is an amino acid involved in the regulation of vascular function and blood flow. Supplementation may improve high blood pressure and erectile dysfunction.
and PDE-5 inhibitors, improves ED when compared to a placebo, though studies using combined yohimbine and PDE-5 inhibitors have only been conducted in animals.
Although it’s often marketed as a fat-loss and performance-enhancing supplement for athletes, there’s no evidence that yohimbine improves strength, increases muscle, or enhances physical performance. Yohimbine does seem to have a lipolytic effect (increases “fat burning”） and may improve body composition or cause regional fat loss when used as a topical ointment
